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Today's podcast was recorded before most of today's front page news was front page news. However, with COVID-19 and the uprising for racial justice, the themes we talk about in this conversation are highly topical. Enjoy…


Richard Kwok is an environmental researcher who studies the effects of environmental pollution on human health. He's also my neighbor, and we met while cleaning up litter and quickly discovered a lot of interests in common.

While the environment doesn't often change our genetics, it can have huge impact on our epigenetics, or how those genes get expressed in our bodies. We can see those changes in methylation and histone markers in our blood, and they can be dramatic. And with advances in data science, certain chipsets can predict health outcomes with sometimes scary accuracy.

This is huge.

Traditionally, we know about the links between environmental factors and disease through self-report. Epidemiologists assess the environment and then find people who've been exposed to it and see how they fare. Do they have more cancer? More heart disease? Impaired respiratory function?

The problem with this methodology is that it can take years or even decades for some environmental exposures to have a clinical impact on health. And public health is rarely well-funded (at least, before the shit hits the fan and some pandemic is ravaging the population, which is arguably always too little too late). So we don't know what's dangerous and lethal until it's been around long enough to do a lot of damage.

When we study epigenetic biomarkers, on the other hand, we can look at a population exposed to, for example, the Blackwater Horizon oil spill in the Gulf of Mexico, and quickly discover the downstream health implications.

In our conversation, Richard guided me through this new field, and shared some of the most robust findings that have the potential to revolutionize public health and health care.

Enjoy, add your voice to the conversation via the comment box below, and please share – that's how we spread our message and spread our roots.

Links

The DOHaD Hypothesis

Minireview: Epigenomic Plasticity and Vulnerability to EDC Exposures, by Cheryl Lyn Walker

Methylation-Based Biological Age and Breast Cancer Risk, by Kresovich et al.

DNA Methylation GrimAge Strongly Predicts Lifespan and Healthspan, by Horvath et al.

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Music

The Plant Yourself Podcast theme music, “Dance of Peace (Sabali Don),” is generously provided by Will Ridenour, a kora player from North Carolina who has trained with top Senegalese musicians.

It can be found on his first CD, titled Will Ridenour.

You can learn about Will, listen to more tracks, and buy music on his website, WillRidenour.com.

Gratitudes

Thanks to Plant Yourself podcast patrons – Kim Harrison – Lynn McLellan – Anthony Dissen – Brittany Porter – Dominic Marro – Barbara Whitney – Tammy Black – Amy Good – Amanda Hatherly – Mary Jane Wheeler – Ellen Kennelly – Melissa Cobb – Rachel Behrens – Christine Nielsen – Tina Scharf – Tina Ahern – Jen Vilkinofsky – David Byczek – Michele X – Elspeth Feldman – Leah Stolar – Allan Kristensen – Colleen Peck – Michele Landry – Jozina – Sara Durkacs – Kelly Cameron – Wayne Pedersen – Janet Selby – Claire Adams – Tom Fronczak – Jeannette Benham – Gila Lacerte – David Donohue – Blair Seibert – Doron Avizov – Gio and Carolyn Argentati – Jodi Friesner – RuthAnn Funderburk – Mischa Rosen – Michael Worobiec – AvIvA Lael – Alicia Lemus – Val Linnemann – Nick Harper – Bandana Chawla – Martha Bergner – Susan Ahmad – Molly Levine – The Inscrutable Harry R – Susan Laverty the Panda Vegan – Craig Covic – Adam Scharf – Karen Bury – Heather Morgan – Kelly Michiya – DeAnne Norton – Bonnie Lynch of Plant Happy Oregon – Sabine Kurtzhals – Nigel Davies – Marian Blum – Teresa Kopel – Julian Watkins – Brid O'Connell – Shannon Herschman – Linda Ayotte – Holm Hedegaard – Isa Tousignant – Connie Haneline – Erin Greer – Alicia Davis – Heather O'Connor – Carollynne Jensen – Sheri Orlekoski of Plant Powered for Health – Karen Smith – Scott Mirani – Karen and Joe Crabtree – Tanya Lewis – Kirby Burton – Theresa Carrell – Kevin Macaulay – Elizabeth Rothschild – Ann Jesse – Sheryl Dwyer – Jenny Hazelton – Valerie Pelletier – Peter W Evans – Colleen Harrison – Justine Divett – Joshua Sommermeyer – Dennis Bird – Darby Kelly – Lori Fanney – Linnea Lundquist – Valarie Hummel – Emily Iaconelli – Levi Wallach – Rosamonde McAtee – Dan Pokorney – Stephen Leinin – Patty DeMartino – Mike and Donna Kartz – Deanne Bishop – Bilberry Elf – Günter Schmid – Marjorie Lewis – Kelly Moulden – Tricia Adams – Ian Cramer – Nancy Sheldon – Lindsey Bashore – Gunn Marit Hagen – Tracey Gulledge – Lara Hedin – Meg from Mamasezz – Rachelle Kennedy – Diana Goldman – Stacey Stokes – Ben Savage – Michael K – Hollie Butler – David Hughes -Coni Rodgers – Claire England – Sally Robertson – Parham Ganchi – Amy Dailey – Brian Tourville – Mark Jeffrey Johnson – Josie Dempsey – Caryn Schmitt – for your generous support of the podcast.

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